Publications of Sarah E. O'Connor

Cheng, J. Z.; Coyle, C. M.; Panaccione, D. G.; O'Connor, S. E.: Controlling a structural branch point in ergot alkaloid biosynthesis. Journal of the American Chemical Society 132 (37), pp. 12835 - 12837 (2010)

Cheng, J. Z.; Coyle, C. M.; Panaccione, D. G.; O'Connor, S. E.: A role for old yellow enzyme in ergot alkaloid biosynthesis. The Journal of Physical Chemistry B 132 (6), pp. 1776 - 1777 (2010)

Coyle, C. M.; Cheng, J. Z.; O'Connor, S. E.; Panaccione, D. G.: An old yellow enzyme gene controls the branch point between Aspergillus fumigatus and Claviceps purpurea ergot alkaloid pathways. Applied and Environmental Microbiology 76 (12), pp. 3898 - 3903 (2010)

Runguphan, W.; Qu, X.; O'Connor, S. E.: Integrating carbon-halogen bond formation into medicinal plant metabolism. Nature 468, pp. 461 - 464 (2010)

Runguphan, W.; Maresh, J. J.; O'Connor, S. E.: Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture. Proceedings of the National Academy of Sciences of the United States of America 106 (33), pp. 13673 - 13678 (2009)

Bernhardt, P.; O'Connor, S. E.: Synthesis and biochemical evaluation of des-vinyl secologanin aglycones with alternate stereochemistry. Tetrahedron Letters 50 (51), pp. 7118 - 7120 (2009)

Bernhardt, P.; O'Connor, S. E.: Opportunities for enzyme engineering in natural product biosynthesis. Current Opinion in Chemical Biology 13 (1), pp. 35 - 42 (2009)

Bernhardt, P.; Yerkes, N.; O'Connor, S. E.: Bypassing stereoselectivity in the early steps of alkaloid biosynthesis. Organic & Biomolecular Chemistry 7 (20), pp. 4166 - 4168 (2009)

Friedrich, A.; Brase, S.; O'Connor, S. E.: Synthesis of 4-, 5-, 6-, and 7-azidotryptamines. Tetrahedron Letters 50 (1), pp. 75 - 76 (2009)

Lee, H.-Y.; Yerkes, N.; O'Connor, S. E.: Aza-tryptamine substrates in monoterpene indole alkaloid biosynthesis. Chemistry & Biology 16 (12), pp. 1225 - 1229 (2009)

Leonard, E.; Runguphan, W.; O'Connor, S. E.; Prather, K. J.: Opportunities in metabolic engineering to facilitate scalable alkaloid production. Nature Chemical Biology 5 (5), pp. 292 - 300 (2009)

Runguphan, W.; O'Connor, S. E.: Metabolic reprogramming of periwinkle plant culture. Nature Chemical Biology 5 (3), pp. 151 - 153 (2009)

Usera, A. R.; O'Connor, S. E.: Mechanistic advances in plant natural product enzymes. Current Opinion in Chemical Biology 13 (4), pp. 492 - 498 (2009)

Maresh, J. J.; Giddings, L.-A.; Friedrich, A.; Loris, E. A.; Panjikar, S.; Trout, B. L.; Stoeckigt, J.; Peters, B.; O'Connor, S. E.: Strictosidine synthase: Mechanism of a Pictet-Spengler catalyzing enzyme. Journal of the American Chemical Society 130 (2), pp. 710 - 723 (2008)

Yerkes, N.; Wu, J. X.; McCoy, E.; Galan, M. C.; Chen, S.; O'Connor, S. E.: Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis. Bioorganic & Medicinal Chemistry Letters 18 (10), pp. 3095 - 3098 (2008)

Bernhardt, P.; McCoy, E.; O'Connor, S. E.: Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle. Chemistry & Biology 14 (8), pp. 888 - 897 (2007)

Galan, M. C.; McCoy, E.; O'Connor, S. E.: Chemoselective derivatization of alkaloids in periwinkle. Chemical Communications 21 (31), pp. 3249 - 3251 (2007)

Chen, S.; Galan, M. C.; Coltharp, C.; O'Connor, S. E.: Redesign of a central enzyme in alkaloid biosynthesis. Chemistry & Biology 13 (11), pp. 1137 - 1141 (2006)

Galan, M. C.; O'Connor, S. E.: Semi-synthesis of secologanin analogues. Tetrahedron Letters 47 (10), pp. 1563 - 1565 (2006)

McCoy, E.; Galan, M.; O'Connor, S. E.: Substrate specificity of strictosidine synthase. Bioorganic & Medicinal Chemistry Letters 16 (9), pp. 2475 - 2478 (2006)